MR1 Tetramer

MR1 complexes bind to T cell receptors on mucosal-associated invariant T (MAIT) cells. MAIT cells have a particular specificity (as determined by the relevant MR1-binding small molecule ligand used), allowing identification, enumeration and isolation of antigen-specific MAIT cells by flow cytometry. MR1 Tetramers show excellent brightness and experimental reproducibility. To avoid the difficulties associated with dissolving and loading the most commonly used ligands, 5-OP-RU and 6-FP, our tetramers come pre-loaded (not available in Australia and the United States). They can also be supplied empty for loading with your ligand of choice.

ProImmune provides fluorescently labeled human MR1 tetramers pre-loaded with 5-OP-RU or 6-FP, or empty for loading with your ligand of choice*.

*In the United States and Australia (a) pre-loaded MR1 products are not are not available and (b) certain uses of unlabeled MR1 products may require additional access rights to intellectual property that are not included with the sale of such products; the responsibility for determining whether such access rights are needed and for obtaining such access rights shall at all times remain with the customer and/or user of such products.